![]() Others have speculated that a pivotal role may be played by negative symptoms or by neurocognitive deficits ( Remington et al., 2011).Ī prominent yet underestimated symptom of schizophrenia is the peculiar interpretation and processing of verbal and non-verbal information, with a great difficulty of patients to put these in the appropriate context. For example, Parnas (2011) suggested that it is marked by autism, i.e., a change in the structures of subjectivity, anomalies of self-experience, disturbed relations to the world, solipsism and isolation. Since Kraepelin and Bleuler, many authors have tried to characterize the “core feature” of schizophrenia, on which all the symptoms depend. Bleuler (1934), for his part, stressed that disturbances of association make up an especially important basic symptom, and indicated that these result in the loss of formal coherence of speech and in disconnected thinking. 3) accentuated a “peculiar destruction of the internal connections of the psychic personality,” as a result of which emotional and volitional aspects of mental life get deregulated. For example, concerning dementia praecox Kraepelin (1913, p. ![]() Seminal descriptions of schizophrenia stress that next to symptoms like hallucinations and delusions, remarkable alterations can be observed in patients’ mental life. Clinical and neurophysiological research implications are discussed. Next, we discuss possible convergences between both approaches, exploring how they might join and inspire one another. In this paper we first review the Lacanian theory of psychosis and neuro-scientific research in the field of symbolization and metaphoric speech. Neuro-scientific contributions have investigated this difficulty suggesting the possibility of interpreting schizophrenia as a semiotic disorder which makes the patients incapable of understanding the figurative meaning of the metaphoric speech, probably due to a dysfunction of certain right hemisphere areas, such as the right temporoparietal junction and the right superior/middle temporal gyrus. Interestingly, in contemporary psychiatry there is growing empirical evidence that schizophrenia is characterized by abnormal interpretation of verbal and non-verbal information, with a great difficulty to put such information in the appropriate context. In particular, he postulated that language makes up the experience of subjectivity and that psychosis is marked by the absence of a crucial metaphorization process. ![]() Starting from the theories of leading psychiatrists, like Kraepelin and de Clérambault, the French psychoanalyst Jacques Lacan (1901–1981) formulated an original theory of psychosis, focusing on the subject and on the structuring role of language. 3Department of Psychoanalysis and Clinical Consulting, Ghent University, Ghent, Belgium.2Child Neuropsychiatry Unit, Neuroscience Department, “Children’s Hospital Bambino Gesù”, Research Hospital, Rome, Italy.1Clinica Psichiatrica, Dipartimento di Medicina dei Sistemi, Università degli Studi di Roma Tor Vergata, Rome, Italy.Michele Ribolsi 1, 2 * Jasper Feyaerts 3 Stijn Vanheule 3
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